

Wheeler is the headliner here for obvious reasons. He's posted a 2.27 ERA with a 40:9 strikeout-to-walk through 43.2 innings, and the only blemish lately was a 4-run, 4-homer outing in LA against the Dodgers — and even then he went 6 innings and only gave up 5 hits. The Phillies are 6-0 in his other starts. Coming off thoracic outlet surgery last September, the velo is down a tick to 94.7 mph but the results obviously haven't suffered.
Giolito has the W-L record working for him at 2-0, but the 4.97 ERA tells you the real story, and his last start was a mess: 2.2 innings, 4 earned, 4 walks, 1 strikeout, 77 pitches. If he can't find the zone early against a Phillies lineup that's been grinding at-bats, this could get out of hand quickly.

- Day-To-DayBlake Hunt (C) — Hunt is dealing with an oblique injury and has been shut down from activity, Kevin Acee of The San Diego Union-Tribune reports.05/08
- 7-Day ILJake Cronenworth (2B) — Cronenworth (concussion) has been running, playing catch and taking light swings in the batting cage, but he remains without a definitive timetable for a return, Kevin Acee of The San Diego Union Tribune reports.05/31
- 10-Day-ILRamon Laureano (LF) — The Padres placed Laureano on the 10-day injured list Tuesday, retroactive to May 31, due to right hip inflammation.06/02
- 10-Day-ILLuis Campusano (C) — Campusano (toe) has been catching bullpens and is swinging pain-free, per MLB.com.05/31
- 15-Day-ILGerman Marquez (SP) — Marquez (forearm) will begin a rehab assignment with Triple-A El Paso on Tuesday.06/02
- 15-Day-ILMatt Waldron (SP) — Waldron (forearm) could take on a bullpen role when he returns from the 15-day injured list, MLB.com reports.05/22
- OutYu Darvish (SP) — Darvish (elbow) revealed Tuesday in a social media post that he has resumed playing catch.05/12
- 60-Day-ILNick Pivetta (SP) — The Padres transferred Pivetta (forearm) to the 60-day injured list Tuesday.06/02
- 60-Day-ILJhony Brito (RP) — Brito (forearm) struck out four batters and allowed one hit and no walks over six shutout innings Friday in a rehab start for Double-A San Antonio.06/01
- 60-Day-ILJoe Musgrove (SP) — Musgrove (elbow) is slated to begin a throwing program soon and is targeting a return after the All-Star break, Dennis Lin of The Athletic reports.05/31
- 60-Day-ILBryan Hoeing (RP) — The Padres transferred Hoeing (elbow) from the 15-day injured list to the 60-day IL on Wednesday.05/08

- Day-To-DayCarson DeMartini (SS)
- Day-To-DayBryan Rincon (SS) — The Phillies promoted Rincon from Single-A Clearwater to High-A Jersey Shore on Aug. 15.05/27
- Day-To-DayRene Pinto (C) — Pinto (undisclosed) began a rehab assignment Monday, Kristie Ackert of the Tampa Bay Times reports.05/08
- Day-To-DayDaniel Robert (RP) — Robert suffered a cardiac incident Sunday while preparing to throw a bullpen session and was taken to a local hospital, Matt Gelb of The Athletic reports.05/08
- Day-To-DayMark Kolozsvary (C) — Kolozsvary (undisclosed) agreed to a minor-league contract with the Phillies on Friday that includes an invitation to spring training, Will Sammon of The Athletic reports.05/08
- 15-Day-ILKyle Backhus (RP) — Backhus (elbow) played catch Wednesday, MLB.com reports.05/14
- suspensionJohan Rojas (CF) — Rojas (shoulder) is starting in center field and batting leadoff in Thursday's Grapefruit League contest against Atlanta, Lochlahn March of The Philadelphia Inquirer reports.05/08
The injury report is brutal for San Diego — Yu Darvish, Joe Musgrove, Nick Pivetta, German Marquez, and Matt Waldron are all on the shelf, which is half a rotation. Jake Cronenworth is still out with a concussion and Ramon Laureano just hit the 10-day IL with hip inflammation. The Phillies are basically healthy on the position-player side, which is doing them no favors in this matchup.
Pinnacle has Philly at -188 with the total sitting at 7.5. That's a fat number on the moneyline, but it's hard to argue when you've got the best pitcher on the mound, the lineup advantage, and a team across the diamond that just can't score. Padres need Giolito to give them something more than 3 innings or this gets ugly fast.